Template
The MOA Brief Template
A six-section template for writing a tight MOA brief. Audience, target, mechanism beats, deliverables, deadline, budget. Used internally on every CDI engagement.
An MOA brief should fit on one page. Anything longer is a sign that scope is unsettled. The six sections we use:
1. Audience. Who is the primary viewer (investor, KOL, MSL, patient)? What do they already know?
2. Target. What gene, protein, complex, or pathway is the hero of the animation? Identify by name and PDB if available.
3. Mechanism beats. The three to five frames the animation must hit (binding, internalization, signaling, downstream effect, outcome).
4. Deliverables. Runtime target, formats (16:9, 9:16, 1:1), with VO or no-sound, language(s).
5. Deadline. Hard date driver (financing announcement, conference, partner meeting) versus soft date (launch quarter).
6. Budget envelope. A real number or a range. Clarity here saves three discovery calls.
If you can write all six in 200 words, you are ready to brief a studio.
Brief us using the template →Checklist
Scientific Accuracy Checklist
A pre-storyboard checklist to verify that an animation is grounded in actual molecular biology. PDB references, mechanism citations, label-language consistency.
Before a storyboard is locked, a scientific reviewer should be able to check off every item below. If any are missing, the storyboard is not ready.
- PDB ID for every depicted protein structure
- Peer-reviewed citation for every mechanism beat
- Label language consistency (mechanism described matches package insert language exactly)
- On-screen labels match style guide (italics for gene names, no italics for protein names)
- Timing of conformational changes matches published kinetics where known
- Cell type accuracy (e.g. CD4+ vs CD8+ T-cells correctly labeled and visualized)
- Tissue context (correct anatomical location for the depicted event)
- Color logic (no use of red for arterial in vein scene, etc.)
- Disclaimer text approved by MLR if applicable
- Reference list in delivery folder for sponsor records
Run this list before storyboard sign-off, not after. Fixing post-storyboard is exponentially more expensive.
See how we run reviews →Guide
Regulatory Dossier Visual Guide
A short guide on when, how, and where to include MOA animation visuals in a regulatory dossier. Format expectations, reference documentation, review-meeting playback.
MOA animations and stillframes appear in regulatory filings more often than people realize. A short guide on when and how to include them:
When to include
- Module 2 summary visuals (especially Section 2.4 nonclinical overview, 2.5 clinical overview)
- Section 14 / clinical study report cover visualizations
- Briefing documents for review committee meetings
- Sponsor-prepared educational materials accompanying the application
What reviewers expect
- Stillframes at print resolution (300 dpi), not just video
- Reference documentation tying every visual claim to a peer-reviewed source
- Conservative depiction (avoid implying mechanism beyond label evidence)
- Clear distinction between depicted and inferred biology
Practical tips
- Deliver an animation as both video and a stillframe gallery (eight to twelve key frames)
- Pair animations with a one-page reference list at the start of the briefing book
- Avoid stylization that obscures structural detail at print resolution
We can produce a review-ready MOA from existing animation assets. Reach out if you have a piece that needs hardening for a regulatory package.
Brief us on a regulatory asset →Playbook
Conference Booth Animation Playbook
How to build an animation that survives a conference floor. Eight-second floor stop, no-sound friendly cuts, multi-screen synchronization.
Conference booth animations have eight to fifteen seconds to stop a passerby. The floor is loud, lit, and full of competing screens. A playbook:
The eight-second stop
- Strong opening visual within the first two seconds (a brand color flash, a striking molecular zoom)
- One bold on-screen claim by second five
- Branded loop-point at second ten so the animation reads cleanly when caught mid-loop
No-sound friendly
- Captions or on-screen labels tell the full story without audio
- Sound design layered separately for the version played at sit-down meetings
- 16:9 booth loop AND 9:16 walk-up cut produced from the same content
Multi-screen
- Synchronized playback across two or more screens via simple timed loop
- Different content per screen for premium booths (e.g. one screen narrative, one screen mechanism deep-dive)
Common mistakes
- Long fade-ins that waste the eight-second window
- Voiceover-dependent narrative that fails on muted floors
- Print-style typography that disappears under booth lighting
Brief us before your next congress →Guide
Investor MOA Production Timeline
A 15 to 25 day timeline for a financing-ready MOA animation. Discovery, script, storyboard, animation, sound, delivery, day by day.
15 to 25 day financing-ready MOA timeline:
Day 1 to 5: Discovery and script
- 30 minute scientific kickoff with founder and scientific lead
- Fixed price agreed upfront after the call
- Script drafted and reviewed in collaboration with your scientific team
- Collaborative review and sign-off with your scientific team
Day 6 to 10: Storyboard and style frames
- Frame-by-frame storyboard with timing
- Storyboard review and sign-off
- Style frame development for look and feel
Day 11 to 18: Animation
- Modeling (proteins, cells, scenes)
- Rigging and motion
- Daily renders for incremental feedback
Day 19 to 21: Compositing and sound
- Voice over recording
- Sound design and mix
- VFX polish and final compositing
Day 22 to 25: Revisions and delivery
- Two revision rounds per step (typically minor; major changes lock at storyboard)
- Final delivery in 16:9 / 9:16 / 1:1 + key frames
Rush variant
- Compresses storyboard and animation phases
- Limited to one revision round per step
- Custom rush budget agreed before kickoff
Brief us before your raise →